Smugglers I'm a little more leanient on, depending on the contraband.  There are stupid prohibitions.  Any true libertarian doesn't believe in smuggling, for a true free market to exist there isn't any such thing as smuggling.

Illegals are definitely a concern, especially on the W coast where containers of people from across the Pacific it's a real issue.

Terrorists?  I'm not sure there are any reasonable concerns in this arena.  I'm not saying it doesn't happen, just that I don't believe it happens enough to be worthy of the same attention as illegal immigration.

Shoot first ask questions later?  That's an uncivilized policy.
Armed drones?  That's just plain cowardice.  If you're going to get violent then you should have the cojones to put your cojones behind the gun.  When you take the horror out of war, you take away an incentive for peace.