Ketosis is often confused with ketoacidosis which is a dangerous condition.

Ketosis on it's own is not dangerous.

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Some clinicians regard ketosis as a dangerous and potentially life-threatening state that stresses the liver and causes destruction of muscle tissues.[9][10][11][dubious – discuss] . Ketogenesis can occur solely from the byproduct of fat degradation: acetyl-CoA. Ketosis, which is accompanied by gluconeogenesis (the creation of glucose de novo from pyruvate), is the specific state with which clinicians are concerned. The anti-ketosis conclusions have been challenged by a number of doctors and advocates of low-carbohydrate diets, who dispute assertions that the body has a preference for glucose and that there are dangers associated with ketosis.[12][13][14] It has been argued that the Inuit lived for thousands of years on a diet that would have been ketogenic, and there are many documented cases of modern humans living in these societies for extended periods of time. This argument does not bring the fact of genetic predisposition, of the Inuit people in the study, to healthfully eat a ketogenic diet, via evolutionary adaptation, caused by environmental stresses.[15] While it is believed by some[who?] that exercise requires carbohydrate intake in order to replace depleted glycogen stores, studies have shown that, after a period of 2–4 weeks of adaptation, physical endurance is unaffected by ketosis, as long as the diet contains high amounts of fat.[15]